This list marks 20 years since we began compiling an annual selection of the year's most important technologies. Some, such as mRNA vaccines, are already changing our lives, while others are still a few years off. Below, you'll find a brief description along with a link to a feature article that probes each technology in detail. We hope you'll enjoy and explore-taken together, we believe this list represents a glimpse into our collective future.

We got very lucky. The two most effective vaccines against the coronavirus are based on messenger RNA, a technology that has been in the works for 20 years. When the covid-19 pandemic began last January, scientists at several biotech companies were quick to turn to mRNA as a way to create potential vaccines; in late December 2020, at a time when more than 1.5 million had died from covid-19 worldwide, the vaccines were approved in the US, marking the beginning of the end of the pandemic. read-more